The Effective of Potassium Sodium Hydrogen Citrate in Treating Uric Acid Stones Using Gut Microbiota and Metabolomics.

RecruitingOBSERVATIONAL
Enrollment

30

Participants

Timeline

Start Date

March 1, 2022

Primary Completion Date

March 30, 2024

Study Completion Date

June 30, 2024

Conditions
Uric Acid Stones
Interventions
DRUG

Potassium sodium hydrogen citrate

"Medication: Potassium sodium hydrogen citrate granules (MADAUS GMBH, Germany, 2.5g/package).~Method: Preprandial urine pH was monitored to maintain an effective range of 6.2 to 6.8. One package should be taken after breakfast, one after lunch, and two after dinner. If the pH falls below 6.2, a half-package dose should be added; if it exceeds 6.8, a half-package dose should be reduced accordingly. Oral medication will be administered for a duration of three months.~Medication requirements: Abstain from alcohol and smoking during treatment period and avoid using any probiotics or drugs that lower uric acid levels."

Trial Locations (1)

215500

RECRUITING

Changshu Hospital Affiliated to Soochow University, Changshu

All Listed Sponsors
lead

Cheng Cao

OTHER