Effect of Colchicine on Perioperative Anti-inflammatory Organ Injury in Cardiac Surgery

PHASE3RecruitingINTERVENTIONAL
Enrollment

768

Participants

Timeline

Start Date

January 28, 2024

Primary Completion Date

August 31, 2026

Study Completion Date

December 30, 2026

Conditions
Inflammatory ResponseCardiac Disease
Interventions
DRUG

Colchicine 0.5 MG

Take 0.5mg of colchicine tablets orally for 3 days before surgery, and continued to take 0.5mg every other day (qod) for 10 days after tracheal extubation.

DRUG

Placebo

Take 0.5mg of starch tablets orally for 3 days before surgery, and continued to take 0.5mg every other day (qod) for 10 days after tracheal extubation.

Trial Locations (1)

210008

RECRUITING

Dong-Jin Wang, Nanjing

All Listed Sponsors
collaborator

First Affiliated Hospital of Zhejiang University

OTHER

collaborator

Jinan Central Hospital

OTHER

collaborator

The First People's Hospital of Changzhou

OTHER

collaborator

Xinhua hospital of ILi in Kazakhstan automomous district

UNKNOWN

collaborator

First Affiliated Hospital of Harbin Medical University

OTHER

collaborator

The Affiliated Hospital of Yangzhou University

UNKNOWN

collaborator

Shandong Provincial Hospital

OTHER_GOV

collaborator

The First People's Hospital of Huai'an

UNKNOWN

collaborator

The First Affiliated Hospital of Shihezi University Medical College

UNKNOWN

collaborator

Affiliated Hospital of Nantong University

OTHER

lead

The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School

OTHER