Comparison of SVF-gel Filling and CO2 Fractional Laser on Atrophic Acne Scar Treatment

NACompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

January 20, 2021

Primary Completion Date

July 20, 2022

Study Completion Date

January 20, 2023

Conditions
Autologous Fat Graft Harvesting, SVF-gel Preparation and FillingCO2 Fractional Laser Treatment by Using Acupulse Device
Interventions
DEVICE

SVF-gel Filling and CO2 fractional laser

"SVF-gel preparation and filling:The autologous fat graft was harvested from the lower abdomen or inner thigh of all subjects. Then the lipoaspirate was centrifuged at 1200g for 3 minutes to obtain Coleman fat in the middle layer. The Coleman fat was then transferred between two syringes until the Coleman fat converted into a uniform emulsion, and then processed by centrifugation at 2000g for 3 min. Finally, the remaining substance under the oil layer was SVF gel. We used a 22G sharp-tip injector to inject the SVF-gel into the dermis of acne scars, and the injected materials were diffusely distributed.~CO2 fractional laser treatment: After local anesthesia, Acupulse device (LUMENIS, US) was used to perform CO2 fractional laser. The laser was operated in DeepFX mode under the parameters of 20-25 MJ energy intensity, 5% coverage. Superficial mode under the parameters of 80-120 MJ energy intensity, 40-60% coverage."

Trial Locations (2)

710032

Acupulse device, Xi'an

Unknown

Acupulse device, Xi'an

All Listed Sponsors
lead

Xijing Hospital

OTHER

NCT06116162 - Comparison of SVF-gel Filling and CO2 Fractional Laser on Atrophic Acne Scar Treatment | Biotech Hunter | Biotech Hunter