44
Participants
Start Date
August 1, 2023
Primary Completion Date
December 31, 2023
Study Completion Date
January 31, 2024
epinephrine
patients will receive epinephrine prepared as 10 ml syringe filled with 10 ml of epinephrine 10 mcg/ml. prepared by drawing 1ml epinephrine 1mg ampule into 9 ml saline then discarding 9 ml and adding another 9 ml saline. now the investigators have 10 ml of epinephrine 10 mcg/ ml (1:100,000), then 10 µg will be given intravenously every 2-minute starting before intubation and continue during and after intubation for 4 times or until the systolic blood pressure (SBP) will be at least 90 mmHg or the mean arterial pressure (MAP) 65 mmHg or greater or after 4th dose of epinephrine and still hypotensive vasopressor (norepinephrine 30 ng /kg/min.) will be added or increased.
isotonic fluid
patients will receive IV bolus isotonic fluid 500 ml
RECRUITING
Ain Shams University Hospitals at Intensive care units department, Cairo
Ain Shams University
OTHER