"Hypovitaminosis D and Metabolic Inflammatory Status in Patients With Obesity"

CompletedOBSERVATIONAL
Enrollment

208

Participants

Timeline

Start Date

January 1, 2018

Primary Completion Date

June 30, 2021

Study Completion Date

June 30, 2021

Conditions
Hypovitaminosis DObesity
Interventions
DIAGNOSTIC_TEST

Vitamin D Plasma Level

Blood test measured in ng/ml

DIAGNOSTIC_TEST

Bioelectrical Impedance Analysis (BIA) technique

Measurements of body composition were conducted with Bioelectrical Impedance Analysis (BIA) technique, asking the participants to stand on the device barefoot to complete the analysis. Among all parameters, BMI, phase angle (PhA), total body water (TBW), extracellular (ECW) and intracellular water (ICW), body fat index, and fat and muscular mass were recorded.

DIAGNOSTIC_TEST

Ferritin

Ferritin plasma levels were measured in μg/L

DIAGNOSTIC_TEST

C reactive protein (CRP)

CRP plasma levels were measured in mg/L

DIAGNOSTIC_TEST

Inflammation-based prognostic scores

Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS), Prognostic Nutritional Index (PNI), Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte ratio (PLR), Lymphocyte-to-monocyte ratio (LMR), Systemic immune-inflammation index (SII) were calculated using blood test results

OTHER

Liver biopsy

A liver biopsy was used to study nonalcoholic steatohepatitis (NASH) and fibrosis according to the Kleiner-Brunt classification

Trial Locations (1)

34100

Silvia Palmisano, Trieste

All Listed Sponsors
lead

University of Trieste

OTHER

NCT06115356 - "Hypovitaminosis D and Metabolic Inflammatory Status in Patients With Obesity" | Biotech Hunter | Biotech Hunter