2,500
Participants
Start Date
January 9, 2024
Primary Completion Date
February 24, 2027
Study Completion Date
August 11, 2027
Ganfeborole
Oral daily dosage of 20mg.
BTZ-043
Oral daily dosage of 1000mg.
Bedaquiline (B)
Oral daily dosage of 400mg for the first 2 weeks, thereafter 100mg daily until end of treatment.
Delamanid (D)
Oral daily dosage of 300mg.
Pretomanid (Pa)
Oral daily dosage of 200mg.
Moxifloxacin (M)
Oral daily dosage of 400mg.
Linezolid (L)
Oral daily dosage of 600mg for the first 8 weeks.
Pyrazinamide (Z)
Oral daily dosage of 1200mg-2000mg depending on weight.
Rifampicin (R)
Oral daily dosage of 450mg-750mg depending on weight.
Isoniazid (H)
Oral daily dosage of 225mg-375mg depending on weight.
Ethambutol (E)
Oral daily dosage of 825mg-1375mg depending on weight.
Delpazolid (DZD)
Oral daily dosage of 1200mg
Quabodepistat (Q)
Oral daily dosage of 30mg
ACTIVE_NOT_RECRUITING
"PMSI Institute of Pneumology Chiril Draganiuc", Chisinau
RECRUITING
TASK Brooklyn, Cape Town
RECRUITING
University of Cape Town Lung Institute, Cape Town
RECRUITING
TASK Eden, George
RECRUITING
NIMR Mbeya, Mbeya
RECRUITING
Kibong'oto Infectious Diseases Hospital, Moshi
RECRUITING
NIMR Mwanza, Mwanza
RECRUITING
Joint Clinical Research Centre, Kampala
RECRUITING
Makerere University Lung Institute, Kampala
ACTIVE_NOT_RECRUITING
National Lung Hospital, Hanoi
ACTIVE_NOT_RECRUITING
Pnth/Oucru, Ho Chi Minh City
Collaborators (2)
Radboud University Medical Center
OTHER
London School of Hygiene and Tropical Medicine
OTHER
University of Oxford
OTHER
Research Center Borstel
OTHER
Lygature
UNKNOWN
TASK Applied Science
OTHER
Vita-Salute San Raffaele University
UNKNOWN
Helmholtz Zentrum Munchen
UNKNOWN
KNCV Tuberculosis Foundation
OTHER
Critical Path Institute
UNKNOWN
European Lung Foundation
UNKNOWN
Instituto de Saude Publica da Universidade do Porto
OTHER
University of Liverpool
OTHER
Institut de Recherche pour le Developpement
OTHER_GOV
University of Hamburg-Eppendorf
OTHER
University of California, San Francisco
OTHER
TB Alliance
UNKNOWN
Find
OTHER
University of Milano
UNKNOWN
University of St Andrews
OTHER
Uppsala University
OTHER
European Respiratory Society
OTHER
Tuberculosis Network European Trialsgroup
NETWORK
Janssen, LP
INDUSTRY
Otsuka Pharmaceutical Development & Commercialization, Inc.
INDUSTRY
German Center for Infection Research
OTHER
LMU University Hospital Munich
UNKNOWN
University of Cambridge
OTHER
GlaxoSmithKline
INDUSTRY
University College, London
OTHER