Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study.

NARecruitingINTERVENTIONAL
Enrollment

75

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Glioblastoma
Interventions
DIAGNOSTIC_TEST

18F-GE-180 PET

PET examination of glioblastoma using 18F-GE-180 PET radio-metabolic marker

DIAGNOSTIC_TEST

Advanced MRI

MRI examination using advanced sequences to characterize tumor microstructure and function

OTHER

Collection of hematopoietic stem cells

Hematopoietic stem cells will be collected by the aspiration of bone marrow during the surgical intervention for tumor resection

OTHER

Blood withdrawal

blood withdrawal for evaluation of plasma biomarkers of inflammation, circulating microvesicles, and RNA

OTHER

Collection of Cancer Stem Cells

Glioblastoma stem cells (GSCs) will be isolated from the tumor

Trial Locations (1)

20089

RECRUITING

IRCCS Istituto Clinico Humanitas, Rozzano

Sponsors
All Listed Sponsors
collaborator

Mediolanum Cardio Research

OTHER

lead

Istituto Clinico Humanitas

OTHER

NCT06113705 - Imaging and Biological Markers for Prediction and Identification of Glioblastoma Pseudoprogression: a Prospective Study. | Biotech Hunter | Biotech Hunter