Transcranial Magnetic Stimulation in Patients With Depression and Non-suicidal Self-injury

NARecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

September 30, 2024

Study Completion Date

February 28, 2025

Conditions
Depressive Disorder, MajorSelf-Injurious Behavior
Interventions
PROCEDURE

Transcranial Magnetic Stimulation (TMS)

The Intermittent Theta Burst Stimulation (iTBS) protocol will be used. This protocol involves bursts of stimulation at the theta frequency range, approximately 5 to 8 Hz. The specific combination utilized combines bursts of pulses at a frequency of 50 Hz, triggered at a rate of 5 Hz. Thus, a burst of 3 pulses is delivered with intervals of 20 ms between them, and this burst is repeated at intervals of 200 ms (i.e., 5 bursts per second). Every second, 15 pulses are delivered.

PROCEDURE

Sham

A stimulator with an arm containing a non-functional replica of the stimulation coil will be utilized. The application procedures will be identical to those of the active group, except that the device simulating the stimulation coil will not generate a magnetic field, only producing sound cues mimicking a stimulus.

Trial Locations (1)

90610-000

RECRUITING

Instituto do Cérebro do Rio Grande do Sul, Porto Alegre

All Listed Sponsors
lead

Brain Institute of Rio Grande do Sul

NETWORK