44
Participants
Start Date
July 13, 2020
Primary Completion Date
March 10, 2022
Study Completion Date
March 10, 2022
Iron oxide nanoparticles treatment Ferumoxytol/H2O2
Participants receive a topical treatment through a root canal irrigation needle containing A mixture of 6mg/mL Ferumoxytol nanoparticles solution mixed with 3% H2O2 for 10 minutes contact time
NaOCl
Participants receive a topical treatment through a root canal irrigation needle containing 3% NaOCl for 10 minutes contact time
NaCl
Participants receive a topical treatment through a root canal irrigation needle containing 0.89% NaCl for 10 minutes contact time
supplementary irrigation
"All canals in all groups were irrigated with 2 mL of 3% NaOCl, followed by ultrasonic irrigant activation for 30s twice.~seconds. This step was repeated once again making the total activation time 1 min and the total contact time of the irrigant 3 min. Upon completion of irrigation, a third bacterial sample (S3) was taken following the deactivation, washing, drying, and sampling steps as described previously"
University of Pennsylvania, Philadelphia
University of Pennsylvania
OTHER