Population Health Approach to Optimizing Medications in Older Adults

NAEnrolling by invitationINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

May 19, 2025

Primary Completion Date

November 24, 2026

Study Completion Date

December 1, 2026

Conditions
Medication Adverse EffectsOlder Adults (65 Years and Older)PolypharmacyPolypharmacy PatientsDeprescribing
Interventions
BEHAVIORAL

Patient-tailored deprescribing assessment and intervention

Patients are identified for enrollment via a risk prediction model and enrolled in a pharmacist-led polypharmacy clinic. The pharmacist will conduct a comprehensive medication review, which will include: medication reconciliation, assessment of patient risk factors (clinical, socioeconomic), identification of potentially inappropriate medications, identification of potential prescribing omissions, shared decision-making with the patient and/or caregiver, and confirmation of the results of the comprehensive medication review with the primary care clinician. Once the primary care clinician has approved the recommendations, the pharmacist will make the appropriate changes to the medication regimen, will provide tailored medication education and counseling (including Motivational Interviewing) and will follow-up with the patient at least once per month via video visit or phone to assess side effects, adverse effects, and provide support.

Trial Locations (1)

90048

Cedars-Sinai Medical Center, Los Angeles

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

Cedars-Sinai Medical Center

OTHER