A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

1,108

Participants

Timeline

Start Date

November 6, 2023

Primary Completion Date

December 6, 2024

Study Completion Date

November 7, 2025

Conditions
Plaque Psoriasis
Interventions
DRUG

TAK-279

Specified drug on specified days.

DRUG

Placebo

Specified drug on specified days.

DRUG

Apremilast

Specified drug on specified days.

Trial Locations (217)

1431

Diagnostic and Consulting Center Aleksandrovska EOOD, Sofia

1463

Diagnostic Consultative Centre - Focus-5 - LZIP EOOD, Sofia

1510

Medical Center Hera EOOD, Sofia

1592

Diagnostic Consultative Center XXVIII - Sofia - EOOD, Sofia

1606

Ambulatory for Specialized Medical Care- Group Practice in Dermatology - Clinic EuroDerma OOD, Sofia

Military Medical Academy Multiprofile Hospital for Active Treatment - Sofia, Sofia

1612

MC Comac Medical - IRN - PPDS, Sofia

2115

MBAL Skin Systems, Doganovo, Elin Pelin

2600

Medical Center Asklepii OOD, Dupnitsa

4032

Debreceni Egyetem Klinikai Kozpont Nagyerdei Campus, Debrecen

5000

Allergo-Derm Bakos Kft- Szolnok-Baross utca 20, Szolnok

5300

Multiprofile Hospital For Active Treatment Dr Tota Venkova, Gabrovo

5400

Medical Center Unimed EOOD, Sevlievo

5800

Medical Center Medconsult Pleven OOD, Pleven

5801

Medical Center Exacta Medica - Vasil Levski 60, Pleven

6300

Diagnostic Consultative Center Sveti Georgi EOOD, Haskovo

6720

Szegedi Tudomanyegyetem, Szeged

7400

Somogy Varmegyei Kaposi Mor Oktato Korhaz, Kaposvár

7632

Pécsi Tudomanyegyetem - Vasvari Pal u., Pécs

9300

Multiprofile Hospital for Active Treatment - Dobrich AD, Dobrich

9700

Vas Varmegyei Markusovszky Egyetemi Oktatokorhaz, Szombathely

10629

FutureMeds - Berlin - PPDS, Berlin

11790

Derm Research Center of NY, Stony Brook

13885

AP-HM- Hôpital de La Timone, Marseille

18101

HaEmek Medical Center, Afula

20354

Dermatologikum Hamburg, Hamburg

23507

Virginia Clinical Research - 6160 Kempsville Cir, Norfolk

24148

Medizinisches Versorgungszentrum DermaKiel GmbH, Kiel

28040

Hospital Clinico San Carlos, Madrid

28046

Hospital Universitario La Paz - PPDS, Madrid

33615

Olympian Clinical Research - 6331 Memorial Hwy, Tampa

35010

Hospital Universitario de Gran Canaria Doctor Negrin, Las Palmas de Gran Canaria

35205

Total Dermatology, Birmingham

45324

Wright State Physicians, Fairborn

46940

Hospital de Manises, Manises

48455

Fachklinik Bad Bentheim, Bad Bentheim

49100

Rabin Medical Center - PPDS, Petah Tikva

52621

The Chaim Sheba Medical Center - PPDS, Ramat Gan

64239

Tel Aviv Sourasky Medical Center Ichilov - PPDS 27004, Tel Aviv

68144

Skin Specialists PC, Omaha

72037

Centre Hospitalier Le Mans, Le Mans

75034

North Texas Center for Clinical Research, Frisco

76031

Hôpital Charles Nicolle-1 Rue de Germont, Rouen

92123

University Clinical Trials, San Diego

100029

China-Japan Friendship Hospital, Beijing

200040

Huashan Hospital Fudan University - PPDS, Shanghai

210029

The First Affiliated Hospital With Nanjing Medical University(Jiangsu Province Hospital), Nanjing

212001

Affiliated Hospital of Jiangsu University, Zhenjiang

310016

Sir Run Run Shaw Hospital Zhejiang University School of Medicine - Qingchun Campus, Hangzhou

330008

The Second Affiliated Hospital of Nanchang University, Nanchang

410013

The Third Xiangya Hospital of Central South University, Changsha

430030

Tongji Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan

450003

Henan Provincial People's Hospital, Zhengzhou

510080

Guangdong Provincial People's Hospital, Guangzhou

610041

West China Hospital Sichuan University, Chengdu

650000

The Second Affiliated Hospital of Kunming Medical University, Kunming

9112002

Hadassah Medical Center- Ein Kerem - PPDS, Jerusalem

35244-2111

Cahaba Dermatology Skin Health Center, Hoover

85006-2722

Medical Dermatology Specialists, Phoenix

85704-7892

Noble Clinical Research, Tucson

72916-6103

Johnson Dermatology Clinic, Fort Smith

71913-6475

Burke Pharmaceutical Research, Hot Springs

90211-1705

Zenith Research, Inc., Beverly Hills

91436-2428

UNISON Clinical Trials (Shahram Jacobs md inc.), Encino

92708-3701

First OC Dermatology Research Inc., Fountain Valley

90805-4587

Long Beach Research Institute, LLC, Long Beach

90017-5310

Metropolis Dermatology Downtown LA - Probity - PPDS, Los Angeles

91325-4122

Northridge Clinical Trials, Northridge

92123-1523

TCR Medical Corporation, San Diego

90404-2216

Dermatology Institute and Skin Care Center, Santa Monica

33122-1902

Revival Research Corporation - Florida - ClinEdge - PPDS, Doral

33136-1003

Florida Academic Centers Research, Miami

33014-5602

San Marcus Research Clinic Inc, Miami Lakes

33027-4714

FXM Research Miramar, Miramar

33172-2741

Lenus Research & Medical Group, Sweetwater

33607-6429

Advanced Clinical Research Institute (ACRI) - Florida, Tampa

30315-2042

Divine Dermatology and Aesthetics, LLC, Atlanta

30342-1418

Advanced Medical Research, PC, Atlanta

31217-3861

Skin Care Physicians of Georgia, Macon

60077-1049

NorthShore Medical Group Dermatology - Skokie, Skokie

47129-2201

DS Research - 1005 E. Lewis & Clark Pkwy Indiana Location, Clarksville

40217-1444

Skin Sciences, PLLC, Louisville

40241-6162

DS Research of Kentucky, Louisville

70605-1213

Dermatology & Advanced Aesthetics, Lake Charles

20850-6363

Lawrence J Green, MD LLC, Rockville

01915

Allcutis Research LLC, Beverly

02301

Beacon Clinical Research LLC, Brockton

48103-9746

David Fivenson MD Dermatology PLLC, Ann Arbor

48109-5360

University of Michigan Hospital - 1500 E Medical Center Dr, Ann Arbor

48326-3396

Oakland Hills Dermatology - 3400 Auburn Rd, Auburn Hills

55432-3134

Minnesota Clinical Study Center, Fridley

89119-5190

Vivida Dermatology - Flamingo Rd - Probity - PPDS, Las Vegas

03801-03804

ALLCUTIS Research, LLC., Portsmouth

08520

Psoriasis Treatment Center of Central New Jersey, East Windsor

10029-6504

Mount Sinai Doctors -234 E 85th St, New York

10075-0385

Sadick Research Group, New York

10467-1402

Montefiore Dermatology - BRANY - PPDS, The Bronx

27710-4000

Duke Dermatology Clinic, Durham

27103-7109

The Skin Surgery Center for Clinical Research - Objective Health - PPDS, Winston-Salem

27157-0001

Wake Forest Baptist Health Department of Dermatology - 4618 Country Club Rd, Winston-Salem

43213-4445

ClinOhio Research Services, Columbus

44124-4005

Apex Clinical Research Center, Mayfield Heights

97239-4501

Oregon Medical Research Center PC, Portland

15213-3403

University of Pittsburgh Medical Center-3601 5th Ave, Pittsburgh

37076-3497

Cumberland Skin Center for Clinical Research - Objective Health - PPDS, Hermitage

37215-2888

Tennessee Clinical Research Center, Nashville

76011-3800

Arlington Research Center, Arlington

77401-3535

UT Physicians Dermatology - Bellaire Station, Bellaire

75231-6077

Modern Research Associates, Dallas

78660-6148

Austin Institute for Clinical Research, Inc. - Pflugerville - ClinEdge - PPDS, Pflugerville

78218-3128

Texas Dermatology and Laser Specialists, San Antonio

78229-3409

Dermatology Clinical Research Center of San Antonio, San Antonio

77479-1001

Houston Center for Clinical Research, LLC, Sugar Land

77598-4927

Center For Clinical Studies, LTD. LLP - 451 N Texas Ave, Webster

Center For Clinical Studies,LTD. LLP - 451 N Texas Ave, Webster

C1012

Conexa Investigación Clínica S.A., Buenos Aires

C1023AAB

STAT Research S.A., Buenos Aires

C1425BEA

Instituto de Neumonologia y Dermatologia, Buenos Aires

C1060ABN

Centro de Investigacion Clínica - CEDIC, Ciudad Autónomade Buenos Aires

T4000

Centro de Investigaciones Médicas Tucumán - PPDS, San Miguel de Tucumán

Unknown

University Multiprofile Hospital for Active Treatment -Dr. Georgi Stranski -Gen. V. Vazov Str 91, Pleven

Royalderm, Warsaw

T3A 2N1

Dermatology Research Institute, Inc. - Probity - PPDS, Calgary

T6G 1C2 Canada

Alberta DermaSurgery Centre - Probity - PPDS, Edmonton

T6H 4J8

VIDA Dermatology - Probity - PPDS, Edmonton

T4N 7C3

CaRe Clinic-Red Deer, Red Deer

R3E 0V9

Wiseman Dermatology Research Inc. - Probity - PPDS, Winnipeg

E3B 1G9

Brunswick Dermatology Centre - Probity - PPDS, Fredericton

L8L 3C3

Lima's Excellence In Allergy And Dermatology Research (Leader) Inc. - Probity - PPDS, Hamilton

L8N 1Y2

Dermatrials Research, Hamilton

N6H 5L5

DermEffects - Probity - PPDS, London

L3P 1X3

Lynderm Research Inc - Probity - PPDS, Markham

L4Y 4C5

DermEdge Research - Probity - PPDS, Mississauga

L6J 7W5

The Centre for Clinical Trials Inc. - Probity - PPDS, Oakville

L1R 1R7

Oshawa Clinic-117 King St, Oshawa

K9J 1Z2

SKiN Centre for Dermatology - Peterborough - Probity - PPDS, Peterborough

L4B 1M5

Centre For Dermatology and Cosmetic Surgery - Probity - PPDS, Richmond Hill

L4C 9M7

Dr. S. K. Siddha Medicine Professional Corporation - Probity - PPDS, Richmond Hill

M3B 0A7

Canadian Dermatology Centre - Probity - PPDS, Toronto

M3H 5Y8

Toronto Research Centre - Probity - PPDS, Toronto

N2J 1C4

Alliance Clinical Trials - Probity - PPDS, Waterloo

N8X 3V6

XLR8 Medical Research - Probity - PPDS, Windsor

H3Z 2S6

Siena Medical Research, Westmount

S7K 0H6

Skinsense Medical Research - 411 2nd Ave N - Probity - PPDS, Saskatoon

030001

First Hospital of Shanxi Medical University, Taiyuan

547 01

Dermamedica, s.r.o. - Kozni Ambulance Nachod, Náchod

741 01

Nemocnice AGEL Novy Jicin a.s, Nový Jičín

702 00

CCR Ostrava s.r.o., Ostrava

150 00

Praglandia s.r.o., Prague

779 00

Dermskin s.r.o., Olomouc

100 00

CLINTRIAL s.r.o., Prague

602 00

Pratia Brno s.r.o. - PRATIA - PPDS, Brno

530 02

Pratia Pardubice a.s. - PRATIA - PPDS, Pardubice

100 34

Fakultni nemocnice Kralovske Vinohrady, Prague

110 00

Prof. MUDr. Petr Arenberger, DrSc. - CRC - PPDS, Prague

01069

Klinische Forschung Dresden GmbH (KFGN) - PRATIA - PPDS, Dresden

01097

Praxis fur Dermatologie and Venerologie, Dresden

07548

SRH Wald-Klinikum Gera GmbH, Gera

161 21

Hospital A.Syggros, Athens

124 62

University General Hospital ''ATTIKON'', Chaïdári

455 00

University Hospital of Ioannina, Loannina

546 43

Hospital Of Skin And Venereal Diseases of Thessaloniki, Thessaloniki

564 29

Papageorgiou General Hospital of Thessaloniki, Thessaloniki

LV-1011

Adoria, Riga

LV-3201

Smite Aija doctor practice in dermatology, venerology, Talsi

LV-3301

Semigallia, Kuldīga

LV-1001

Riga 1st Hospital, Riga

LV-1003

Health Center 4, Center of Diagnostics, Riga

J. Kisis, Riga

LV-1009

Veseliba un estetika, Riga

LV-1013

Health Center 4, Clinic of Dermatology, Riga

60-101

Solumed Centrum Medyczne, Poznan

61-293

Twoja Przychodnia PCM, Poznan

30-033

Centrum Medyczne ALL-MED, Krakow

31-501

Krakowskie Centrum Medyczne - FutureMeds - PPDS, Krakow

51-685

WroMedica, Wroclaw

20-573

Luxderm Specjalistyczny Gabinet Dermatologiczny Dorota Krasowska, Lublin

67-100

Twoja Przychodnia Nowosolskie Centrum Medyczne sp. z o.o, Nowa Sól

90-338

Centrum Terapii Wspolczesnej, Lódz

96-100

ClinMedica Research, Skierniewice

08-110

ETG Siedlce - PPDS, Siedlce

96-500

RCMed Oddzial Sochaczew, Sochaczew

01-142

Clinical Research Group Sp. z o.o, Warsaw

02-672

AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Warszawie, Warsaw

02-677

ETG Warszawa - PPDS, Warsaw

03-291

FutureMeds - Targowek - PPDS, Warsaw

87-100

MICS Centrum Medyczne Torun - MICS - PPDS, Torun

15-351

NZOZ Osteo Medic SC Artur Racewicz Jerzy Supronik, Bialystok

89-600

Centrum Medyczne Chojnice - PRATIA - PPDS, Chojnice

80-546

Centrum Badan Klinicznych PI-House sp. z o.o., Gdansk

81-537

AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Gdyni, Gdynia

40-040

AES - DRS - Synexus Polska Sp. z o.o. Oddzial w Katowicach, Katowice

40-611

Centrum Medyczne Angelius Provita, Katowice

40-648

Pro Familia Altera Sp. z o.o., Katowice

32-700

Centrum Uslug Medycznych MaxMed, Bochnia

82-300

Ambulatorium Barbara Bazela, Elblag

57-300

Globe Badania Kliniczne Spólka z o.o. - Klodzko, Klodzko Dolnoslaskie

30-727

MCM Krakow - PRATIA - PPDS, Krakow

31-559

Diamond Clinic, Krakow

20-314

ETG Lublin - PPDS, Lublin

10-117

ETYKA Osrodek Badan Klinicznych, Olsztyn

86-031

DermoDent Centrum Medyczne Aldona Czajkowska Rafał Czajkowski, s.c., Osielsko

51-503

dermMEDICA Sp. z o.o, Wroclaw

27-400

Dermedic Jacek Zdybski, Ostrowiec Świętokrzyski

Ostrowieckie Centrum Medyczne, Ostrowiec Świętokrzyski

00909-3004

GCM Medical Group, PSC -62 Calle Jose Marti, San Juan

08915

Hospital Universitario Germans Trias i Pujol, Badalona

08041

Hospital de La Santa Creu i Sant Pau, Barcelona

HP11 2QW

Velocity Clinical Research, High Wycombe - PPDS, High Wycombe

IG1 4HP

4 Medical Clinical Solutions (4MCS) Swinton - PPDS, Ilford

PR7 7NA

Accellacare of Yorkshire, Chorley

M6 8HD

Salford Royal Hospital - PPDS, Salford

E11 1NR

Whipps Cross Hospital, London

HA1 3UJ

Accellacare of Northamptonshire, Harrow

N12 8BU

Velocity Clinical Research, North London - PPDS, London

HA6 2RN

Accellacare - North London Clinical Studies Centre, Northwood

BD5 0NA

St Luke's Hospital, Bradford

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Takeda

INDUSTRY