99mTc-MY6349 SPECT/CT Imaging in Trop2-positive Triple-negative Breast Cancer

NARecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

September 13, 2023

Primary Completion Date

October 1, 2026

Study Completion Date

December 31, 2026

Conditions
Breast Cancer
Interventions
DIAGNOSTIC_TEST

99mTc-MY6349 SPECT/CT scan

Triple-negative breast cancer patients underwent 99mTc-MY6349 SPECT/CT imaging to observe the binding ability of this tracer to Trop2 in the tumor and the uptake of the drug by the tumor, combined with the pathological expression level of Trop2 in the patient's lesions and 18F-FDG PET/CT imaging uptake to evaluate the efficacy of 99mTc-MY6349 in the diagnosis of triple-negative breast cancer; at the same time, combined with the treatment effect of patients using the anti-Trop2 targeted antibody gosatuzumab, the analysis of 99mTc-MY6349 SPECT/CT imaging prediction of prognosis in patients with triple-negative breast cancer treated with gosatuzumab.

Trial Locations (1)

100730

RECRUITING

Peking Union Medical College Hospital, Beijing

All Listed Sponsors
lead

Peking Union Medical College Hospital

OTHER