500
Participants
Start Date
August 1, 2021
Primary Completion Date
August 1, 2030
Study Completion Date
December 30, 2032
MRI scan
Brain MRI scan to evaluate the integrity of the nervous system; lower limb muscle MRI scan to evaluate fat infiltration in skeletal muscles of the lower limb
Electrocardiography
Standard 12-lead electrocardiography or Holter monitoring performed to assess cardiac conduction abnormalities and arrhythmias in patients with DM1.
Pulmonary function test
Comprehensive pulmonary function testing including spirometry to assess respiratory muscle weakness and restrictive lung disease in DM1 patients.
Huashan Hospital, Shanghai
Chinese People's Liberation Army General Hospital, Beijing
Peking University First Hospital, Beijing
First Affiliated Hospital of Chongqing Medical University, Chongqing
Fujian Medical University Union Hospital, Fuzhou
Southern Hospital of Southern Medical University, Guangzhou
The Third Hospital of Hebei Medical University, Shijiazhuang
Wuhan University People's Hospital, Wuhan
Zhongda Hospital Southeast University, Nanjing
The First Affiliated Hospital of Soochow University, Suzhou
The First People's Hospital of Yancheng, Yancheng
The First Affiliated Hospital of Nanchang University）, Nanchang
The First Bethune Hospital of Jilin University, Changchun
Chifeng Municipal Hospital, Chifeng
Qilu Hospital of Shandong University, Jinan
Children's Hospital of Fudan University, Shanghai
First Hospital of Shanxi Medical University, Taiyuan
Xi'an Gaoxin Hospital, Xi’an
Xi'an People's Hospital, Xi’an
Sichuan Provincial People's Hospital, Chengdu
The General Hospital of Western Theater Command, Chengdu
Yunnan Provincial People's Hospital, Kunming
Huashan Hospital
OTHER