Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction

CompletedOBSERVATIONAL
Enrollment

136

Participants

Timeline

Start Date

October 1, 2020

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2023

Conditions
Small Bowel ObstructionContrast Media Adverse Reaction
Interventions
DIAGNOSTIC_TEST

Enteral contrast challenge

Contrast agent, volume of contrast, and contrast dilution were not standardized across sites due to the differences in hospital specific formularies; otherwise, the protocol was standardized across sites. Diatrizoate meglumine (osmolality of 1940 mOsm/kg) was used preferentially at eight sites and Ioversol (702 mOms/kg) at one site. Patients received 30-200ml (based on age or weight depending on site) of enteral contrast followed by X-rays at 8-12 hours and 24 hours after contrast administration.

Trial Locations (9)

75390

Children's Medical Center of Dallas, Dallas

80045

Children's Hospital Colorado, Aurora

84113

Primary Children's Hospital, Salt Lake City

85006

Phoenix Children's Hospital, Phoenix

90027

Children's Hospital Los Angeles, Los Angeles

92123

Rady Children's Hospital, San Diego

94609

UCSF Benioff Children's Hospital, Oakland

97239

Oregon Health Sciences University, Portland

98105

Seattle Children's Hospital, Seattle

All Listed Sponsors
collaborator

Children's Hospital Los Angeles

OTHER

collaborator

University of California, San Francisco

OTHER

collaborator

Oregon Health and Science University

OTHER

collaborator

Rady Children's Hospital, San Diego

OTHER

collaborator

Phoenix Children's Hospital

OTHER

collaborator

Primary Children's Hospital

OTHER

collaborator

Children's Medical Center Dallas

OTHER

collaborator

Seattle Children's Hospital

OTHER

lead

Children's Hospital Colorado

OTHER

NCT06101719 - Use of a Water Soluble Contrast-Based Protocol to Assist in the Management of Pediatric Adhesive Small Bowel Obstruction | Biotech Hunter | Biotech Hunter