NCT06094816View on ClinicalTrials.gov

Forebrain Electroneutral Transporters in Salt-sensitive Hypertension: an MRI Study

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

March 5, 2024

Primary Completion Date

January 31, 2028

Study Completion Date

July 31, 2028

Conditions
Salt-Sensitivity of Blood Pressure
Interventions
DRUG

Furosemide (Diuretic)

The diuretic furosemide will be given during a 3% hypertonic saline infusion to examine blockade of the NKCC2.

OTHER

Hypertonic Saline Infusion

3% Hypertonic saline infusion to acutely increase sodium and osmolality

Trial Locations (1)

19713

RECRUITING

University of Delaware, Newark

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Delaware

OTHER