RFA or Chemical Neurolysis of the Genicular Nerves Compared to Conservative Treatment for Knee Pain Caused by OA

NARecruitingINTERVENTIONAL
Enrollment

192

Participants

Timeline

Start Date

November 27, 2023

Primary Completion Date

November 1, 2026

Study Completion Date

November 1, 2026

Conditions
Osteo Arthritis KneeKnee Pain Chronic
Interventions
PROCEDURE

Diagnostic genicular nerve block

Diagnostic block will be done with 1,5ml of Lidocaine 2% at the 3 target sites: the superomedial, the superolateral and the inferomedial genicular nerve.

PROCEDURE

Genicular nerve block with Radiofrequency Ablation (RFA)

"Genicular nerve block with RFA will be performed at 3 target sites: the superomedial, the superolateral and the inferomedial genicular nerve.~Radiofrequency ablation (RFA) is performed by creating two RFA lesions at the 3 treatment sites (6 lesions in total) after local anesthesia with 1,5ml lidocaine 2%. The lesions are made by heating the 5mm active tip of the needle to 80°C for 90 seconds."

PROCEDURE

Genicular nerve block with Phenol 6%

"Genicular nerve block with Phenol 6% will be performed at 3 target sites: the superomedial, the superolateral and the inferomedial genicular nerve.~Chemical ablation with phenol is done by injection of 1 ,5ml of phenol 6 % at the 3 target sites after infiltration with contrast dye to rule out intravascular injection. Because infiltration with phenol is painless, prior infiltration of the target site with al local anaesthetic is not necessary."

Trial Locations (2)

1624NP

RECRUITING

Dijklander Ziekenhuis, Hoorn

4708AE

NOT_YET_RECRUITING

Bravis Ziekenhuis, Roosendaal

All Listed Sponsors
collaborator

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

OTHER

collaborator

Bravis Hospital

OTHER

lead

Dijklander Ziekenhuis

OTHER