20
Participants
Start Date
June 1, 2024
Primary Completion Date
June 30, 2024
Study Completion Date
June 30, 2025
Botulinum toxin type A injection
The BT injection will be performed by a doctor with experience in this therapy, with 100 Units (U) of type A BT, bilaterally, in the flexor muscle of the thigh, once, with replacement of the same ampoules with saline in controls. To the Patient assessments will take place over 4 months, weekly by telephone using a questionnaires on freezing and the notion of clinical improvement (FOGQ and SCGIC, respectively) and monthly in person with objective assessments using the MDS-UPDRS scales - part III motor assessment, Timed Up \& Go and Two Minute Walk.
Maria Margarida Grilo da Silva Dias, Lisbon
Centro Hospitalar de Lisboa Central
OTHER