Effectiveness of Botulinum Toxin in Freezing of Gate in Parkinson's Disease Walking in Parkinson's Disease.

NANot yet recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

June 1, 2024

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2025

Conditions
Freezing of GateParkinson DiseaseBotulinum Toxin
Interventions
DRUG

Botulinum toxin type A injection

The BT injection will be performed by a doctor with experience in this therapy, with 100 Units (U) of type A BT, bilaterally, in the flexor muscle of the thigh, once, with replacement of the same ampoules with saline in controls. To the Patient assessments will take place over 4 months, weekly by telephone using a questionnaires on freezing and the notion of clinical improvement (FOGQ and SCGIC, respectively) and monthly in person with objective assessments using the MDS-UPDRS scales - part III motor assessment, Timed Up \& Go and Two Minute Walk.

Trial Locations (1)

1150-199

Maria Margarida Grilo da Silva Dias, Lisbon

All Listed Sponsors
lead

Centro Hospitalar de Lisboa Central

OTHER

NCT06094309 - Effectiveness of Botulinum Toxin in Freezing of Gate in Parkinson's Disease Walking in Parkinson's Disease. | Biotech Hunter | Biotech Hunter