Hypotensive Anesthesia for Orthognathic Surgery

PHASE4RecruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

March 4, 2025

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Hypotensive AnesthesiaOrthognathic Surgery
Interventions
DRUG

Dexmedetomidine

1 mcg/kg will be administered intravenously over 10 minutes; followed by maintenance infusion of 0.2 to 1 mcg/kg/hour.

DRUG

Nicardipine

1 mg will be administered intravenously and increase by 0.5-1 mg if the initial dose is ineffective, to a maximum of 15 mg / hour or

DRUG

Labetalol

20 - 80 mg will be administered intravenously at 10-minute intervals to maximum of 300 mg;

Trial Locations (1)

02118

RECRUITING

Boston Medical Center, Boston

Sponsors
All Listed Sponsors
lead

Boston Medical Center

OTHER