Traditional Chinese Medicine Ultrasonic Atomization Treatment for Dry Eye Disease

NARecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

July 28, 2024

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2025

Conditions
Dry Eye Syndromes
Interventions
DRUG

TCM ultrasonic atomization treatment with herbal Compound Decoction (CD)

"The subjects will receive TCM ultrasonic atomization treatment with the ultrasonic nebulizer (WH-2000, YueHua, China) 6 days a week, once daily, 10 minutes per session, for 4 weeks. The solution for atomization of the CD group is TCM compound decoction.~The prescription of atomization solution in the CD group contains Honeysuckle flower (金銀花) 5g, Chrysanthemum flower (菊花) 5g, Pale betterflybush flower (密蒙花) 5g, Mild mint herb (薄荷) 5g, Barbary wolfberry fruit (枸杞子) 10g, and Ophiopogon japonicus (麥冬) 5g.~Subjects will be treated with hypromellose 0.3% w/v eye drops four times per day too."

DRUG

TCM ultrasonic atomization treatment with Dendrobii Caulis (DC)

"The subjects will receive TCM ultrasonic atomization treatment with the ultrasonic nebulizer (WH-2000, YueHua, China) 6 days a week, once daily, 10 minutes per session, for 4 weeks. The solution for atomization of the DC group is Dendrobii Caulis extracts.~The prescription of the DC group contains Dendrobium (石斛) 35g.~Subjects will be treated with hypromellose 0.3% w/v eye drops four times per day too."

DRUG

TCM ultrasonic atomization treatment with Houttuynia Cordata (HC)

"The subjects will receive TCM ultrasonic atomization treatment with the ultrasonic nebulizer (WH-2000, YueHua, China) 6 days a week, once daily, 10 minutes per session, for 4 weeks. The solution for atomization of the HC group is Heartleaf Houttuynia Herb extracts.~The prescription of the HC group contains Heartleaf Houttuynia Herb(魚腥草) 35g.~Subjects will be treated with hypromellose 0.3% w/v eye drops four times per day too."

DRUG

Placebo TCM ultrasonic atomization treatment (PA)

"The subjects will receive TCM ultrasonic atomization treatment with the ultrasonic nebulizer (WH-2000, YueHua, China) 6 days a week, once daily, 10 minutes per session, for 4 weeks. The solution for atomization of the PA group is low-concentration compound decoction (5%) same with the CD group.~Subjects will be treated with hypromellose 0.3% w/v eye drops four times per day too."

DRUG

Artificial Tears (AT)

The subjects will receive lubricant eye drop (Hypromellose 0.3% w/v Eye Drops) four times per day only.

Trial Locations (4)

000000

RECRUITING

The Chinese University of Hong Kong Eye Centre (CUHKEC), Kowloon

RECRUITING

Prince of Wales Hospital, Shatin

Unknown

RECRUITING

Hong Kong Eye Hospital, Kowloon

000 000

RECRUITING

The CUHK Medical Centre (CUHKMC), Shatin

All Listed Sponsors
lead

Chinese University of Hong Kong

OTHER