Effects of Acute Exercise and Ibuprofen on Symptoms, Immunity, and Neural Circuits in Bipolar Depression

PHASE1/PHASE2RecruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

March 12, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Bipolar Depression
Interventions
OTHER

Exercise Session

30 min cycling on bicycle ergometer at 60% peak power output

DRUG

Ibuprofen 800 mg

A single oral dose of Ibuprofen

OTHER

Rest

Resting for 30 min in chair

DRUG

Placebo

Matched placebo

Trial Locations (1)

74136

RECRUITING

Laureate Institute for Brain Research, Tulsa

All Listed Sponsors
lead

Laureate Institute for Brain Research, Inc.

OTHER