Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata

NANot yet recruitingINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

December 31, 2023

Primary Completion Date

March 31, 2024

Study Completion Date

June 30, 2024

Conditions
Alopecia Areata
Interventions
DRUG

Methotrexate

A standard derma pen 12 pins with of 0,5 mm depth was used, dermapen as a tool of infusion of our treatments works in a few ways to target hair loss, firstly by breaking down the scar tissue that covers or compromises the hair follicles which are not growing, stimulating new hair growth and also by enhancing infusion of mesotherapy ingredients to increase hair follicle size and therefore hair volume ,here we will use it by stamping technique, the procedure was practically painless and therefore no local anesthesia was used, however For those who will not want to tolerate pain, topical anesthesia with 2% lignocaine, under occlusion will applied, the patients will be followed up for 6 months after full course of treatment. Then we will apply methotrexate topically (25 mg/ml) on half of the scalp at a dose of 0.02ml/cm2

DRUG

Triamcinolone Acetonide

A standard derma pen 12 pins with of 0,5 mm depth was used, will use it by stamping technique, the procedure was practically painless and therefore no local anesthesia was used, however For those who will not want to tolerate pain, topical anesthesia with 2% lignocaine, under occlusion will applied, the patients will be followed up for 6 months after full course of treatment. Then Triamcinolone acetonide 40 mg/1ml after microneedking at dose 5mg/ml concentration;1/8/ 1:7 dilution

Trial Locations (1)

Unknown

Al-Azhar University, Asyut

All Listed Sponsors
lead

Al-Azhar University

OTHER

NCT06088147 - Methotrexate Versus Triamcinilone Acetonide in Treatment of Recalcitrant Alopecia Areata | Biotech Hunter | Biotech Hunter