Pulmonary Disease Among Patients With Systemic Lupus Erythematosus

Enrolling by invitationOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

August 15, 2023

Primary Completion Date

September 30, 2024

Study Completion Date

January 1, 2026

Conditions
Lupus Erythematosus, SystemicPulmonary Disease
Interventions
OTHER

Multidisciplinary discussion

"Multidisciplinary discussion: Participants will be diagnosed and categorized in regards of pulmonary disease on basis of medical record, PFT, HRCT, and questionnaires.~PFT: Participants will undergo body plethysmography (with diffusion) and six-minute walk test.~Analysis of circulating biomarkers: We will store glasses with serum and glasses with plasma and analyse them for circulating biomarker.~Questionnaires: Participants will complete Danish versions of three questionnaires.~* Saint George's Respiratory Questionnaire Interstitial Pulmonary Fibrosis~* Systemic Lupus Activity Questionnaire~* Lupus Impact Tracker~Review of medical record and clinical investigation with focus on SLE and pulmonary disease.~Thoracic and diaphragmatic ultrasound: The participants will undergo a 14 zone protocol, and be evaluated for b-lines and pleural thickening/irregularities. Diaphragm function will be evaluated according to the M-mode method, area method, and for thickening."

Trial Locations (1)

DK 5000

Odense University Hospital, Odense

All Listed Sponsors
collaborator

Karolinska University Hospital

OTHER

collaborator

Esbjerg Hospital - University Hospital of Southern Denmark

OTHER

collaborator

Vejle Hospital

OTHER

collaborator

Sonderborg Hospital

OTHER_GOV

lead

Odense University Hospital

OTHER