Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

November 1, 2024

Study Completion Date

December 30, 2024

Conditions
Postoperative Pain
Interventions
DRUG

Dexmedetomidine

Under strict aseptic conditions, a lumbar puncture will be performed with selective technique in sitting position at L2-3 or L3-4 interspaces with midline approach using a 25-G Quincke's needle. After achieving the free flow of cerebrospinal fluid, the study drug will be injected into the subarachnoid space, immediately after injection the patient will be asked for supine position.

DRUG

Midazolam

1 mg midazolam intrathecal administration

DRUG

Bupivacain

20 mg bupivacaine intrathecal administration

All Listed Sponsors
lead

Assiut University

OTHER