Ondanstron Weekly vs Every 3 Weeks for Prevention of Nausea and Vomiting Induced by Chemotherapy Combined With PD-1 Blockade

NARecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

November 30, 2025

Study Completion Date

November 30, 2027

Conditions

Nausea With Vomiting Chemotherapy-Induced

Interventions

DRUG

Ondansetron every 3 weeks

Ondansetron, Po, 24mg/d, 3 days' application every 3 weeks

DRUG

Aprepitant

aprepitant, Po, 125mg/d, 1day' application every 3 weeks

DRUG

Dexamethasone

dexamethasone, iv, 10mg/d, 1day' application every 3 weeks

DRUG

Ondansetron weekly

Ondansetron, Po, 24mg/d, 3 days' application weekly

Trial Locations (1)

RECRUITING

Hubei Cancer Hospital, Wuhan

All Listed Sponsors

lead

Hubei Cancer Hospital

OTHER