Glucocorticoid Treatment in Transaortic Valve Replacement to Reduce the Incidence of Conduction Disturbances (GLUCO-TAVR).

PHASE4RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

August 12, 2023

Primary Completion Date

September 1, 2024

Study Completion Date

September 1, 2024

Conditions
Heart BlockAortic StenosisBundle-Branch Block
Interventions
DRUG

Methylprednisolone

The intervention group will recieve 7 mg/kg/day (or a maximum of 500 mg/day) of intravenous Methylprednisolone an hour before TAVR followed by 15 mg / 12h of Prednisone during 5 days after the intervention (starting 24h after the administration of Methylprednisolone).

OTHER

Placebo

Saline solution

Trial Locations (1)

03010

RECRUITING

General University Hospital of Alicante, Alicante

All Listed Sponsors
lead

Hospital General Universitario de Alicante

OTHER