Comparison of Epithelial Lining Fluid and Blood Pharmacokinetics and Pharmacodynamics of Intravenous and Intravenous Plus Nebulized Polymyxin B in Multidrug Resistant Bacteria Ventilator-associated Pneumonia Patients

RecruitingOBSERVATIONAL

Enrollment

Participants

Timeline

Start Date

July 1, 2023

Primary Completion Date

July 1, 2024

Study Completion Date

August 1, 2024

Conditions

Polymyxin BVentilator-associated PneumoniaMultidrug Resistant Bacterial InfectionPharmacogenomic Drug Interaction

Interventions

DRUG

nebulized polymyxin B

The experimental group received intravenous combined nebulization of polymyxin B

Trial Locations (1)

RECRUITING

Zhongda Hospital Affiliated to Southeast University, Nanjing

All Listed Sponsors

lead

Southeast University, China

OTHER