NCT06072768View on ClinicalTrials.gov

Dynamic Treatment Regiments for Glucocorticoid Tapering

PHASE2RecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

March 9, 2023

Primary Completion Date

March 1, 2029

Study Completion Date

March 1, 2030

Conditions
Rheumatoid Arthritis
Interventions
DRUG

15-day taper prednisone

The 15-day taper group will assess the effect of an approximately 50% oral prednisone dose reduction over 15 days, and will be followed for an additional 15 days after the last dose reduction.

DRUG

150-day taper prednisone

The 150-day taper group will assess the effect of reducing oral prednisone by 1 milligram (mg) every 30 days over 150 days, and will be followed for an additional 30 days after the last dose reduction.

Trial Locations (2)

48109

RECRUITING

University of Michigan, Ann Arbor

48105-2303

RECRUITING

VA Ann Arbor Healthcare System, Ann Arbor, MI, Ann Arbor

All Listed Sponsors
collaborator

University of Michigan

OTHER

lead

VA Office of Research and Development

FED