NCT06070649View on ClinicalTrials.gov

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

PHASE1RecruitingINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

August 4, 2025

Primary Completion Date

August 1, 2026

Study Completion Date

August 1, 2026

Conditions
Alcohol Use Disorder (AUD)Alcohol-Related DisordersAlcohol Use
Interventions
DRUG

0.3mg/kg/min Dimethyltryptamine + Normal Saline infusion

Infusion

DRUG

0.2 mg/kg/min + Dimethyltryptamine 0.01mg/kg/min infusion

Infusion

DRUG

25 mg Diphenhydramine (5 min) + Normal Saline

Infusion

Trial Locations (1)

06519

RECRUITING

Connecticut Mental Health Center, New Haven

All Listed Sponsors
collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

Yale University

OTHER