Radiosurgery Treatment for Spasticity Associated With Stroke, SCI & Cerebral Palsy

NARecruitingINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

October 12, 2023

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Spasticity as Sequela of StrokeSpastic Cerebral PalsySpasticity, Muscle
Interventions
RADIATION

stereotactic radiosurgery (SRS) dorsal root rhizotomy radiomodulation

"Patients will be simulated in the supine position in an immobilization apparatus deemed by the treating physician to be appropriate for the patient being able to comfortably maintain position for the duration of treatment. All patients will be simulated and treated using free breathing. Prescription dose is 50 Gy delivered in a single fraction to the target volume, prescribed to whatever isodose line produces optimal falloff (but not less than a 50% isodose line; dmax \<100Gy) .~All radiosurgery treatment will utilize the Varian Edge, Varian TrueBeam STx, or CyberKnife system"

OTHER

Sham

Patients will be simulated in the supine position in an immobilization apparatus deemed by the treating physician to be appropriate for the patient being able to comfortably maintain position for the duration of treatment. All patients will be simulated and treated using free breathing.

Trial Locations (2)

32789

NOT_YET_RECRUITING

Renaissance Institute of Precision Oncology & Radiosurgery, Winter Park

43210

RECRUITING

Ohio State University Wexner Medical Center, Columbus

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Varian Medical Systems

INDUSTRY

lead

Ohio State University

OTHER