Prehabilitation in Pancreatic Surgery

NARecruitingINTERVENTIONAL
Enrollment

238

Participants

Timeline

Start Date

July 14, 2023

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2027

Conditions
Pancreatic CancerPeriampullary CancerFrailty SyndromeMalnutritionPerioperative/Postoperative Complications
Interventions
OTHER

Multimodal Prehabilitation

Preoperative multimodal intervention including exercise training, nutritional therapy and psychosocial counseling, aimed at preventing or attenuating surgery-driven functional decline. A personalized intervention program will be prescribed based on specific physical, nutritional and psychological conditions recognized during the multimodal assessment. Patients will follow a 2 to 3-day per week exercise program for 4-6 weeks including endurance, resistance, and inspiratory muscle training, tailored to individual preferences and clinical conditions. Based on dietary habits and nutritional status, a certified nutritionist will provide a comprehensive diet management program. A food-based intervention with a balanced macronutrient composition coupled with oral nutritional supplements will be prescribed to achieve the estimated daily energy and protein requirements. Patients will meet with a psychologist to explore their emotional and psychosocial needs related to their current situation.

Trial Locations (1)

20132

RECRUITING

San Raffaele Hospital, Milan

All Listed Sponsors
collaborator

Ministero della Salute, Italy

OTHER

lead

IRCCS San Raffaele

OTHER