351
Participants
Start Date
March 31, 2023
Primary Completion Date
August 19, 2024
Study Completion Date
August 19, 2024
AK111
AK111 regimen 1- subcutaneous injection at week 0,1,2, 3,4 and every 4 weeks thereafter until week 48. The primary endpoint will be evaluated at week 12 and followed up to week 56.
AK111
AK111 regimen 2- subcutaneous injection at week 0,1,2, 3,4 and every 4 weeks thereafter until week 48. The primary endpoint will be evaluated at week 12 and followed up to week 56.
Placebo
Placebo- subcutaneous injection at week 0,1,2, 3, 4 and week 8. AK111 regimen 2-subcutaneous injection every 4 weeks from week 12 to week 48. The primary endpoint will be evaluated at week 12 and followed up to week 56.
The first affiliated hospital of Bengbu Medical College, Bengbu
The first affiliated hospital of wannan medical college, Wannan
Affiliated hospital of Chongqing Three Gorges Medical College, Chongqing
Chongqing traditional Chinese medicine hospital (Daomenkou branch), Chongqing
Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou
Shenzhen People's hospital, Shenzhen
The first affiliated hospital of Hainan Medical university, Haikou
Nanyang First People's hospital national third class a hospital, Nanyang
Renmin hospital of Wuhan University Hubei general hospital, Wuhan
Yichang central People's hospital, Yichang
The third Xiangya hospital of Central South University, Changsha
The frist People's hospital of Lianyungang, Lianyungang
Dermatology Hospital of China Union Medical University, Nanjing
The affiliated hospital of Xuzhou Medical University, Xuzhou
Yancheng No.1 People's hospital, Yancheng
Dermatology hospital of Jiangxi province, Nanchang
The second hospital of Dalian Medical University, Dalian
Second hospital of Shanxi Medical University, Taiyuan
Tangdu hospital of the Fourth Military Medical University, Tanggu
West China school of medicine, West China hospital of Sichuan University, Chengdu
Tianjin academy of traditional Chinese medicine affiliated hospita, Tianjin
Tianjin Medical University general hospital, Tianjin
Hangzhou first People's hospital, Hangzhou
The first hospital of Jiaxing, Jiaxing
Ningbo Huamei hospital, University of Chinese Academy of Sciences, Ningbo
The first affiliated hospital of Wenzhou Medical University, Wenzhou
Beijing friendship hospital, Capital Medical University, Beijing
Peking University third hospital, Beijing
Guangdong provincial people's hospital, Guangdong
Affiliated hospital of Chengde Medical University, Hebei
The second affiliated hospital of Harbin Medical University, Heilongjiang
Xiangya hospital Central South University, Hunan
Huashan hospital, Fudan University, Shanghai
Shanghai skin disease hospital, Shanghai
Lead Sponsor
Akeso
INDUSTRY