Early-life MRI Biomarkers of Longer-term Respiratory Morbidity in Infants Born Extremely Preterm (EMBLEM)

RecruitingOBSERVATIONAL
Enrollment

319

Participants

Timeline

Start Date

March 30, 2024

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Lung FunctionBPD - Bronchopulmonary Dysplasia
Interventions
DIAGNOSTIC_TEST

Magnetic Resonance Imaging (MRI)

Magnetic Resonance Imaging (MRI) is a non-invasive medical imaging technique that uses powerful magnets and radio waves to generate detailed images of the body's internal structures. The MRI intervention includes using a specialized MRI machine and lung imaging protocol.

DIAGNOSTIC_TEST

Echocardiogram

"An echocardiogram, often called an echo, is a non-invasive medical test that uses high-frequency sound waves (ultrasound) to create real-time images of the heart's structure and function. It provides valuable information about the heart's size, shape, and function."

DIAGNOSTIC_TEST

Lung ultrasound

Lung ultrasound is a non-invasive imaging technique that employs high-frequency sound waves (ultrasound) to visualize the structures and conditions of the lungs. It is particularly valuable for diagnosing and monitoring lung-related conditions, such as pneumonia, pleural effusions, and pulmonary edema. The lung ultrasound intervention involves using an ultrasound machine equipped with a specialized probe gently placed on the chest to capture detailed images of the lungs and adjacent structures.

Trial Locations (4)

K1H 8L1

RECRUITING

The Children's Hospital of Eastern Ontario, Ottawa

M5G 1X5

RECRUITING

Mount Sinai Hospital, Toronto

H3T 1C5

ACTIVE_NOT_RECRUITING

CHU-Sainte Justine, Montreal

H4A 3J1

RECRUITING

Montreal Children's Hospital, Montreal

All Listed Sponsors
collaborator

The Hospital for Sick Children

OTHER

collaborator

MOUNT SINAI HOSPITAL

OTHER

collaborator

Hannover Medical School

OTHER

collaborator

St. Justine's Hospital

OTHER

collaborator

Montreal Children's Hospital of the MUHC

OTHER

lead

Children's Hospital of Eastern Ontario

OTHER