Cardioneuroablation vs Pulmonary Vein Isolation in Treatment of Paroxysmal Atrial Fibrillation

NANot yet recruitingINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

January 31, 2024

Primary Completion Date

January 31, 2028

Study Completion Date

June 30, 2029

Conditions
Atrial Fibrillation Paroxysmal
Interventions
PROCEDURE

Cardioneuroablation of right anterior ganglionated plexus

Right anterior ganglionated plexus will be localized using anatomical approach. Radiofrequency energy will be delivered until heart rate acceleration \>30% is achieved or if radiofrequency time exceeds 120 seconds.

PROCEDURE

Pulmonary vein isolation

Application sites near the ostia of pulmonary veins will be determined. Radiofrequency energy will be delivered using point-by-point technique. After applications, the acute PVI endpoint will be confirmed by the elimination of PV potentials and lack of capture during pacing from the ablation lines.

All Listed Sponsors
lead

St. Joseph's Centre, Poland

OTHER

NCT06058468 - Cardioneuroablation vs Pulmonary Vein Isolation in Treatment of Paroxysmal Atrial Fibrillation | Biotech Hunter | Biotech Hunter