Making ART Work Among Brazilian Youth

NARecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

April 30, 2026

Study Completion Date

April 30, 2026

Conditions
HivAdherence, Medication
Interventions
BEHAVIORAL

Experimental: Making ART Work

A culturally tailored, theoretically grounded provider-facilitated group-based social support intervention (4 sessions) that emphasizes a collective approach to ART adherence and includes establishing a common understanding of ART, identifying potential barriers to ART adherence with a focus on social and structural barriers (e.g., stigma, relationship influences, family support, economic stressors), developing practical strategies to increase self-esteem and self-efficacy to enhance ART adherence, and generating and maintaining peer norms and support for ART adherence within one's social group. These sessions will include SGM youth-specific video vignettes that address the social/contextual realities faced by SGM YLWH in Brazil. Lastly, the intervention includes daily SMS text messaging that serve as both reminders and cognitive cues to take medication as prescribed.

BEHAVIORAL

Standard of Care

Prior to randomization, all participants will meet briefly with a counselor to assess current needs for standard HIV primary care and referrals to social and/or health (including mental health) services. If participants do not have a primary HIV care provider, they will be linked to a provider at INI-Fiocruz or their preferred clinic, where they can access free HIV care through the no-cost universal access program of the Brazilian Public Health System. Additionally, the counselor will provide necessary referrals as needed, e.g., for social, general health and/or mental health services. Additionally, in order to provide a baseline level of standardized adherence information, all participants will receive a brief adherence educational session, which consists of a review of medications and recommended dosing, adherence expectations, toxicity expectations, and medication misperceptions.

Trial Locations (1)

Unknown

RECRUITING

Evandro Chagas National Institute of Infectious Diseases (INI) Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

University of California, Los Angeles

OTHER

collaborator

Oswaldo Cruz Foundation

OTHER

collaborator

National Institute of Mental Health (NIMH)

NIH

lead

Brown University

OTHER