Physiological Versus Right Ventricular Outcome Trial Evaluated for Bradycardia Treatment Upgrades

NARecruitingINTERVENTIONAL
Enrollment

155

Participants

Timeline

Start Date

September 25, 2023

Primary Completion Date

May 1, 2026

Study Completion Date

August 31, 2026

Conditions
Pacing-Induced CardiomyopathyHeart Failure
Interventions
DEVICE

Physiological Pacing Upgrade (Conduction System Pacing or Biventricular Pacing)

The approach for physiological pacing upgrade will be either His bundle pacing or left bundle pacing at the operator's discretion. If both of these are not achieved biventricular pacing will be performed.

DEVICE

Continued RV Pacing (Right Ventricular Pacing)

Right ventricular pacing (apical or septal lead locations as per the implanting physicians' normal practice).

Trial Locations (12)

Unknown

RECRUITING

Royal Papworth Hospital, Cambridge

RECRUITING

St. Richard's Hospital - University Hospitals Sussex, Chichester

RECRUITING

University Hospitals Coventry and Warwickshire NHS Trust,, Coventry

RECRUITING

Croydon University Hospital - Croydon Health Services, Croydon

RECRUITING

Glenfield Hospital, Leicester

RECRUITING

Hammersmith Hospital, London

RECRUITING

King's College Hospital, London

RECRUITING

St Bartholomew's Hospital - Barts Health NHS Trust, London

RECRUITING

Oxford University Hospitals, Oxford

RECRUITING

University Hospitals Southampton, Southampton

RECRUITING

Great Western Hospitals, Swindon

RECRUITING

Worthing Hospital - University Hospitals Sussex, Worthing

All Listed Sponsors
lead

Imperial College London

OTHER