Evaluation of Autogenous Demineralized Dentin Graft Vs Autogenous Bone Graft in Management of Intrabony Defects

PHASE4RecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

July 17, 2024

Primary Completion Date

January 31, 2025

Study Completion Date

March 31, 2025

Conditions
Intrabony Periodontal Defect
Interventions
BIOLOGICAL

Autogenous Demineralized Dentin Graft

The participant's own freshly extracted tooth will be cleaned from periodontal ligaments, cementum, soft tissue attachment, caries, or restorations (if present) and have their crown decapitated, using a high- speed fine finishing stone and saline irrigation. The pulp chamber and root pulp will be cleaned by split opening the root and cleaning it out using a high-speed diamond bur. Subsequently, teeth will be ground, and demineralized using a hand bone mill. Then the particles will be prepared by demineralization of tooth particles in 0.6N hydrochloric acid5 for 30 min then washed twice in saline and dried with sterile gauze. Then it will be used as a graft for the intra-bony defect after modified minimally invasive surgical technique.

BIOLOGICAL

Autogenous Bone Graft

Modified minimally invasive surgical technique (M-MIST) will be performed in the intra-bony defects, with autogenous bone graft placement. The graft will be harvested from the retromolar area using automatic chip maker (ACM) bur and a hand bone mill will be used to grind the chips into particles, then it will be placed in the defect.

Trial Locations (1)

Unknown

RECRUITING

Faculty of Dentistry, Cairo University, Cairo

All Listed Sponsors
lead

Cairo University

OTHER