Multi-parametric MRI Evaluation of Renal Graft Performance After Living Donor Donation.

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

May 7, 2024

Primary Completion Date

September 30, 2027

Study Completion Date

September 30, 2027

Conditions
Renal Insufficiency, Chronic
Interventions
RADIATION

multiparametric MRI

"For the living donor, multiparametric MRI will be added in the day hospital: at the pre-transplant assessment and at the 12-month post-transplant assessment.~For the recipient: multiparametric MRI will be added in the day hospital at the time of the systematic assessment at 1 month post-transplant, and will be added in the day hospital at the time of the 12-month post-transplant assessment."

PROCEDURE

kidney graft biopsy

Biopsy of the graft itself prior to transplantation in the recipient.

BIOLOGICAL

blood samples

"For donors who are not selected to donate their kidney, a total of 2 mL of blood will be collected at inclusion.~For donors eligible to donate, a total of 4 mL of blood will be collected (at inclusion and at 12 months post-transplant).~For recipients, a total of 26 mL of blood will be collected (pre-transplant, 1 month and 12 months post-transplant)."

BIOLOGICAL

urine specimens

"For donors who are not selected to donate their kidney, a total of 15 mL of urine will be collected at inclusion.~For donors eligible to donate, a total of 50 mL of urine will be collected (at inclusion and at 12 months post-transplant).~For recipients, a total of 65 mL of urine will be collected (pre-transplant, 1 month and 12 months post-transplant)."

Trial Locations (1)

69003

RECRUITING

Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER