Efficacy of Injectable Vitamin D Supplementation in Females With Polycystic Ovary Syndrome

PHASE1RecruitingINTERVENTIONAL
Enrollment

142

Participants

Timeline

Start Date

January 1, 2024

Primary Completion Date

June 30, 2026

Study Completion Date

December 31, 2026

Conditions
Anovulatory Infertility
Interventions
DRUG

Vitamin D

"Intervention Group Initial 12 weeks;~* VD supplementation (600,000 IU I/M) once during the study period~* Elemental calcium 1000 mg/day From 12-24 weeks: Standard PCOS;~* Glucophage XR 750 mg once at dinner for 15 days then twice daily~* Capsule Progeffik 100 mg once at night every 3 weeks, then 1 week off~* Calcium 1000 mg/day"

OTHER

Active Comparator

"Active Comparator (Group B; n=71):~Initial-- 12 weeks;~* Standard PCOS;~* Glucophage XR 750 mg once at dinner for 15 days then twice daily~* Capsule Progeffik 100 mg once at night every 3 weeks, then 1 week off From 12- 24 weeks~* VD supplementation (600,000 IUI/M) once during the study period~* Calcium 1000 mg/day~* Standard PCOS Continued"

Trial Locations (1)

75500

RECRUITING

Aga Khan University Hospital, Karachi

All Listed Sponsors
collaborator

Pakistan Science Foundation

OTHER

lead

Aga Khan University

OTHER