Revitalization of Traumatized Immature Permanent Teeth

RecruitingOBSERVATIONAL
Enrollment

72

Participants

Timeline

Start Date

October 1, 2023

Primary Completion Date

September 1, 2028

Study Completion Date

September 1, 2030

Conditions
Apical PeriodontitisTrauma
Interventions
OTHER

revitalization

The main idea behind revitalization is to firstly disinfect the root canal and subsequently attract or transplant mesenchymal stem cells from the (remaining) dental pulp and apical papilla (in case of immature permanent teeth) into the root canal. More specifically, this therapy is not based on mechanical and (aggressive) chemical debridement as in conventional root canal treatment but is supported by the pillars of tissue engineering: stem cells, growth factors and a scaffold .

Trial Locations (1)

9000

RECRUITING

Ghent University, Ghent

All Listed Sponsors
collaborator

University Ghent

OTHER

collaborator

University of Erlangen-Nürnberg

OTHER

collaborator

University of Regensburg

OTHER

collaborator

University of Coimbra

OTHER

lead

Universitaire Ziekenhuizen KU Leuven

OTHER