NCT06039566View on ClinicalTrials.gov

NAC vs Placebo on Opioid Use for Hysterectomy

PHASE3RecruitingINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

November 30, 2023

Primary Completion Date

November 25, 2026

Study Completion Date

December 9, 2026

Conditions
Hysterectomy
Interventions
DRUG

IV N-acetylcysteine

N-acetylcysteine (NAC) 150 mg/kg (Max dose 15,000 mg) through an IV that will run for 60 minutes at the start of the procedure

DRUG

IV Placebo

Placebo 0 mg/kg (placebo: 0.45% NaCl or D5W) through an IV that will run for 60 minutes at the start of the procedure.

Trial Locations (1)

29425

RECRUITING

Medical University of South Carolina, Charleston

All Listed Sponsors
lead

Medical University of South Carolina

OTHER