Novel Cardiovascular Biomarkers in Patients With Kidney Disease

Not yet recruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

November 1, 2023

Primary Completion Date

November 1, 2025

Study Completion Date

November 1, 2026

Conditions
Haemodialysis ComplicationMajor Adverse Cardiac Events
Interventions
DIAGNOSTIC_TEST

Cardiac Biomarkers

Blood samples will be collected at baseline (within 6 weeks of dialysis start), at 6 months post-commencement and 12 months post-commencement of haemodialysis. The blood sampling will be mid-week samples taken at the dialysis start for haemodialysis patients, with a similar approach for the PD controls. For the CKD controls, the blood samples will be scheduled around routine clinic attendance, adhering where possible to the time intervals for HD cases and PD controls.

DIAGNOSTIC_TEST

Lipidomics

Blood samples will be collected at baseline (within 6 weeks of dialysis start), at 6 months post-commencement and 12 months post-commencement of haemodialysis. The blood sampling will be mid-week samples taken at the dialysis start for haemodialysis patients, with a similar approach for the PD controls. For the CKD controls, the blood samples will be scheduled around routine clinic attendance, adhering where possible to the time intervals for HD cases and PD controls.

DIAGNOSTIC_TEST

Proteomics

Blood samples will be collected at baseline (within 6 weeks of dialysis start), at 6 months post-commencement and 12 months post-commencement of haemodialysis. The blood sampling will be mid-week samples taken at the dialysis start for haemodialysis patients, with a similar approach for the PD controls. For the CKD controls, the blood samples will be scheduled around routine clinic attendance, adhering where possible to the time intervals for HD cases and PD controls.

All Listed Sponsors
lead

Liverpool University Hospitals NHS Foundation Trust

OTHER_GOV

NCT06037759 - Novel Cardiovascular Biomarkers in Patients With Kidney Disease | Biotech Hunter | Biotech Hunter