Post-Extubation Assessment of Clinical Stability in ELBW Infants

RecruitingOBSERVATIONAL
Enrollment

20

Participants

Timeline

Start Date

October 29, 2024

Primary Completion Date

December 31, 2025

Study Completion Date

January 31, 2026

Conditions
Extremely Low Birth Weight Infants
Interventions
DEVICE

Oxygen saturation probe

The high-accuracy oxygen saturation signal will be continuously acquired for 168 hours post extubation from a separate pulse oximeter (Radical-7®, Masimo ROOT platform, MasimoCorp, Irvine, LA).

DEVICE

Near infrared spectroscopy sensors

The cerebral and splanchnic regional oxygen saturation signals will be acquired continuously for 168h post extubation using two near infrared spectroscopy sensors (Masimo ROOT platform, MasimoCorp, Irvine, LA), one placed on the forehead for cerebral oxygenation and one on the abdomen (for splanchnic oxygenation).

DEVICE

Electrical impedance tomography

"The regional lung ventilation will be measured using Electrical Impedance Tomography (TIMPEL, USA) at three time points:~* From 1 hour pre-extubation to 2 hours post extubation (total 3 hours)~* Between 24 and 48 hours post extubation (total 3 hours)~* Between 72 and 96 hours post extubation (total 3 hours)"

Trial Locations (2)

H3T 1C5

RECRUITING

Centre Hospitalier Universitaire Sainte-Justine, Montreal

H4A 3J1

RECRUITING

McGill University Health Center, Montreal

All Listed Sponsors
collaborator

St. Justine's Hospital

OTHER

lead

McGill University Health Centre/Research Institute of the McGill University Health Centre

OTHER