Neurocognitive Impact of Different Irradiation Modalities for Patients With Grade I-II Skull Base Meningioma:

NARecruitingINTERVENTIONAL
Enrollment

108

Participants

Timeline

Start Date

September 13, 2023

Primary Completion Date

September 30, 2038

Study Completion Date

June 30, 2039

Conditions
MeningiomaRadiation Toxicity
Interventions
RADIATION

Normo-fractionated intensity-modulated brain irradiation with or without stereotactic positioning

Patients receiving normo-fractionated intensity-modulated brain irradiation with or without stereotactic positioning (IMRT, VMAT, Tomotherapy…)

RADIATION

Hypo-fractionated stereotactic brain irradiation

Patients receiving hypo-fractionated stereotactic brain irradiation

RADIATION

Normo-fractionated proton therapy brain irradiation

Patients receiving normo-fractionated proton therapy brain irradiation

OTHER

Cognitive assessment by a trained neuropsychologis

Participants without any meningioma, cancer history or neurological comorbidities will undergo cognitive assessment by a trained neuropsychologist, similarly as for patients

Trial Locations (3)

14000

RECRUITING

centre François Baclesse, Caen

Unknown

NOT_YET_RECRUITING

Centre Guillaume le Conquérant, Le Havre

NOT_YET_RECRUITING

Centre Henri Becquerel, Rouen

All Listed Sponsors
collaborator

Région Normandie

OTHER_GOV

lead

Centre Francois Baclesse

OTHER