NCT06034405View on ClinicalTrials.gov

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

RecruitingOBSERVATIONAL
Enrollment

1,663

Participants

Timeline

Start Date

September 19, 2023

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2028

Conditions
Lumbar Spinal StenosisCardiac AmyloidosisATTR Amyloidosis Wild TypeATTR Gene MutationATTRV122I AmyloidosisCardiomyopathy, Hypertrophic
Interventions
DIAGNOSTIC_TEST

Tc99-PYP or Tc99-HDMP Scan

Difference in ATTR-CA prevalence between subjects with TTR and indeterminate amyloid deposits in their spine by myocardial uptake of Tc99-PYP.

Trial Locations (6)

10032

RECRUITING

Columbia University Irving Medical Center, New York

44195

RECRUITING

Cleveland Clinic, Cleveland

55905

ACTIVE_NOT_RECRUITING

Mayo Clinic, Rochester

90211

RECRUITING

Cedars-Sinai Medical Center, Beverly Hills

02111

RECRUITING

Tufts Medical Center, Boston

02359

RECRUITING

Boston Medical Center, Boston

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

Columbia University

OTHER