Efficacy of Conventional Dose Protocol vs Low Dose Protocol Albumin Use in Patients With Cirrhosis and High Risk Spontaneous Bacterial Peritonitis

NARecruitingINTERVENTIONAL
Enrollment

300

Participants

Timeline

Start Date

October 10, 2023

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Liver CirrhosisSpontaneous Bacterial Peritonitis
Interventions
BIOLOGICAL

20% High Dose Albumin

"A\]. Patients in the conventional albumin Arm will receive Human Albumin 20% 1.5 g/kg body weight (Maximum 100g) on day 1 after the diagnosis, followed by 1 g/kg bodyweight (Maximum 100g)on day 3 along with standard medical therapy.~Duration of albumin over 24 hours."

OTHER

Standard Medical Treatment

Standard Medical Treatment

BIOLOGICAL

20% Reduced Dose Albumin

"B\]. Patients in the low dose albumin Arm will receive Human Albumin 20% 1.0 g/kg body weight (Maximum 100g) on day 1 after the diagnosis, followed by 0.5 g/kg bodyweight (Maximum 100g) on day 3 along with standard medical therapy.~Duration of albumin over 24 hours."

Trial Locations (1)

110070

RECRUITING

Institute of Liver & Biliary Sciences, New Delhi

All Listed Sponsors
lead

Institute of Liver and Biliary Sciences, India

OTHER