Evaluation of Abemaciclib and Radiation Therapy Before Surgery for the Treatment of High-Risk Adipocytic Retroperitoneal Sarcoma

PHASE1RecruitingINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

March 19, 2025

Primary Completion Date

March 3, 2027

Study Completion Date

March 3, 2029

Conditions

Retroperitoneal Sarcoma

Interventions

DRUG

Abemaciclib

Given PO

PROCEDURE

Computed Tomography

Undergo CT

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

RADIATION

Radiation Therapy

Undergo radiation therapy

PROCEDURE

Therapeutic Surgical Procedure

Undergo surgery

Trial Locations (1)

RECRUITING

Fred Hutch/University of Washington Cancer Consortium, Seattle

All Listed Sponsors

collaborator

Eli Lilly and Company

INDUSTRY

lead

Fred Hutchinson Cancer Center

OTHER