Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

June 1, 2020

Primary Completion Date

May 31, 2022

Study Completion Date

August 1, 2023

Conditions
Gastrointestinal Tumor
Interventions
DEVICE

Water-filtered infrared A radiation whole-body hyperthermia (HECKEL 3000MT-4T, Germany)

The patients were treated with whole-body hyperthermia (HECKEL 3000MT-4T, Germany)) on days 1 and 8 of each hyperthermia combined with immune checkpoint inhibitor treatment cycle along with administration of tislelizumab (BeiGene, China) 200 mg on day 2 (24 hours after the hyperthermia at day 1).

DRUG

tislelizumab (BeiGene, China) combined with PD-1 inhibitor

The patients were treated with whole-body hyperthermia (HECKEL 3000MT-4T, Germany)) on days 1 and 8 of each hyperthermia combined with immune checkpoint inhibitor treatment cycle along with administration of tislelizumab (BeiGene, China) 200 mg on day 2 (24 hours after the hyperthermia at day 1).

Trial Locations (1)

Unknown

Zhejiang Hospital, Hangzhou

All Listed Sponsors
collaborator

Zhejiang Hospital

OTHER

lead

Pengyuan Liu

OTHER

NCT06022692 - Hyperthermia Combined With Immune Checkpoint Inhibitor Therapy for Advanced Gastrointestinal Tumours | Biotech Hunter | Biotech Hunter