"A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or Fragile (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa."

PHASE2RecruitingINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

November 28, 2023

Primary Completion Date

September 30, 2026

Study Completion Date

May 31, 2029

Conditions
Soft Tissue Sarcoma
Interventions
RADIATION

Hypofractionated Radiation Therapy

The Hypofractionated Intensity-Modulated Radiation Therapy will be delivered in 5 fractions of 6 Gy each on the Planning Target Volume (PTV). The total dose of 30 Gy will be administered in approximately 1 week.

PROCEDURE

Conservative treatment

A wide en bloc resection is required (amputation is excluded) while ensuring the best functional preservation. The surgical procedure will take place about 1,5 to 2 months after the end of the radiation therapy.

Trial Locations (11)

Unknown

RECRUITING

Institut Bergonie, Bordeaux

RECRUITING

Centre Oscar Lambret, Lille

RECRUITING

Chu de Limoges, Limoges

RECRUITING

Centre Leon Berard, Lyon

RECRUITING

Institut Regional Du Cancer de Montpellier, Montpellier

NOT_YET_RECRUITING

Institut Curie, Paris

RECRUITING

Chu de Poitiers, Poitiers

RECRUITING

Institut de Cancerologie de L'Ouest, Saint-Herblain

RECRUITING

Chu de Toulouse, Toulouse

RECRUITING

IUCT-O, Toulouse

RECRUITING

Institut Gustave Roussy, Villejuif

All Listed Sponsors
lead

Institut Claudius Regaud

OTHER