Olfactory and Trigeminal Functions in Patients With Multiple Sclerosis: Case-control Study

Not yet recruitingOBSERVATIONAL
Enrollment

200

Participants

Timeline

Start Date

October 30, 2024

Primary Completion Date

July 30, 2025

Study Completion Date

December 30, 2026

Conditions
Multiple Sclerosis
Interventions
DIAGNOSTIC_TEST

TDI

Sniffin' Sticks Threshold and Identification Test

DIAGNOSTIC_TEST

Trigeminal Test

Test the trigeminal smell answer by a device that releases air and a substance that stimulates the trigeminal response

DIAGNOSTIC_TEST

Cognitive Evaluation by Montreal Cognitive Assessment

Montreal Cognitive assessment

DIAGNOSTIC_TEST

Anxiety and Depression questionnaire

Specific test to evaluate patient's mood

DIAGNOSTIC_TEST

Visual Analogue Scale Ratings

"* Smell ability (How is your sense of smell right now? 0 cannot smell, 1-3 severe impairment, 4-6 moderate impairment, 7-9 mild impairment, 10 normal)~* Nasal breathing (How well can you breathe through your nose right now? 0 complete nasal obstruction, 1-3 severe impairment, 4-6 moderate impairment, 7-9 mild impairment, 10 normal)"

DIAGNOSTIC_TEST

Quality of smell Questionnaire

Patients will answer to a validated questionnaire

Trial Locations (1)

95121

Arianna Di Stadio, Catania

All Listed Sponsors
collaborator

University of Roma La Sapienza

OTHER

collaborator

Hospital General Universitario Santa Lucia

OTHER

collaborator

Klinik und Poliklinik fur Kinderheilkunde

OTHER

lead

University of Catania

OTHER

NCT06020937 - Olfactory and Trigeminal Functions in Patients With Multiple Sclerosis: Case-control Study | Biotech Hunter | Biotech Hunter