25
Participants
Start Date
June 1, 2023
Primary Completion Date
December 31, 2027
Study Completion Date
December 31, 2027
Allogenic B7-H3 CAR-γδT cell(QH104)
"Dose escalation (3+3) : dose 1 (1 × 10\^7 CAR+cells) , dose 2 (3 × 10\^7 CAR+cells), dose 3 (6× 10\^7 CAR+cells), once every 4 weeks via an Ommaya reservoir or intrathecal administration.~Dose expansion 1: dose of RP2D, once every 4 weeks via an Ommaya reservoir or intrathecal administration.~Dose expansion 2: 3 × 10\^7 CAR+cells, every two weeks for three consecutive months, then changed to once every 4 weeks via an Ommaya reservoir or intrathecal administration."
RECRUITING
Dushu Lake Hospital Affiliated to Soochow University, Suzhou
Dushu Lake Hospital Affiliated to Soochow University
OTHER